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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c0ca424a442d335401031ff9fff0cea378d26949447695e97fde943f77ad5b9' 
  AND token = 'Q2bmJ2OEY5VA0f8EqpJ+NuzYR414DZDxHcvnlLBdM8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}