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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4cb85bc88bde774519e4f059b996ca6b73b0d54939520b1bfe0dd911f33b71f' 
  AND token = '8uZv2spBuUSf4FKlphkDK1bCa0oGKoG5Xw4pTE8wTLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}