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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3420fb4d7394e1760e3de9dbed81c907b26543f1a5dea2986a423875edcd86d0' 
  AND token = '3Hc1kGGu9cgMCDzn7svRibHGxpmbEeoBxxvr+OY/YeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}