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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75f5dc1e96ff3243ecb821b194fccbb68927e9e10db58edeb175334bd66df411' 
  AND token = 'eR4rpXpBlDB3e+RiW/9RFiRCpVx/P2tVVA9GUodl8uA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}