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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46742f9d1d5561728f7420a1148c1c5b8a44ed4ae22b48f5fe7d2f276b6b1181' 
  AND token = '1tOD35pwlsiK+Zjb5bNJpJt/qBIfqLx/mhtwjH2kkTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}