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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb5109bbf793d78377e4aaf0784774f3a98b10597c1e77a021f9d74fc20ab5f9' 
  AND token = 'DWFQkbTBENgyB77uhUSbTu/cm546tQ5bEwrYvCOO8/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}