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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c26cdc302e1c5633b27f4c2e1e7dccd80c00ea06c788ffe69e5a070777cd5a58' 
  AND token = 'MtZ+jkJDv2xP7u5fHTZylKgVFw9T4Em/IZDFxAXNB6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}