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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca8c2cc1e33e395c78120cbd3cede4a045eee9cee561efb288c546641c28f10c' 
  AND token = 's5OuvrYz/F4Dnj3y7cgyNBmJG0LsoWpIGEoVGdrEZ0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}