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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46a1717161b6f916fbbc64b50d035a1abbd02d088e6370edc68ff4e67c7af219' 
  AND token = 'PW22CiPomu2FLRhbNTzgW6eA0mUS4xGr1f/lXB+/L5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}