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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c97ad7ed99d5c409fe4082afc34ad63d7dc5169be1490ae84d44a2fd972b6747' 
  AND token = 'vPIhd/w/16rulTJ/G39P1Ady3H5Zs4YP4VOte5L4Hko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}