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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b248fd2c5409cad129defcbd4dbb5bebc4462acc8eacb8f257ab9806754f7cf6' 
  AND token = 'eEgcEiQyHcPWvdaXwY3czMf3XjIFbZdLxYiuS5yBtKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}