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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '460547c30a8503613410a5e4c9815194b4e6d3df80b162190a4c1b060cc7a5a4' 
  AND token = 'zcbOo41gowR38zS7qL7LT10EtzQJ7R8Jn3iD47xa4SU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}