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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dd1e624fc85b359ab5713f3ad9596c3be19d1b48cb16ac679887c6c188f9061' 
  AND token = 'c8VEbZKui9JJWBiIq+G4Gk1DBAMcTYDl9ofYxYETKkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}