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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e89791e46849c6b06b81135b82e0d3639fe8e17cb70c65a102e488778f68d33' 
  AND token = 'RtgcQoEZKPFNnzHegObulV+zvayzdwKxap++bbXnh0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}