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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b495d747256945758b23c1c90e3bca6199256fc951917726a11ea07a7d842ab1' 
  AND token = 'b5JtGIDuT7lNtDPTOvBlnxU44DKFjWZzaUVlEK6+8S4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}