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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a7ed32a4a68a5fe9f9cda8086e07194f8574b925c1e43e16a57fa232f6730d1' 
  AND token = 'ZJoOTDe6ic0VuL0ZKByH7y7w9n+B9lt3rc6sqltwx/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}