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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42fc9caf6e9cf0ecfa3c66d64e09528ccb360a7dce619215cfffff48aea330f5' 
  AND token = 'lRlJPwI9DEBbzcRk0PE/qfrGV1FEu0e6lenzChRec2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}