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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11b12355672b0905a93495735b4bdfa98e22a6ef1330a621e1d9170c1fb1779d' 
  AND token = 'ljsoKeejgx9VJ8KvvN9Rr2B8eayimsBJ5kj+c3WyKzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}