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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49580d7fd21105caba1bc59a70553baa8c6e5b4ff913a67dbcbba8a7e5594761' 
  AND token = '93EIfUuStDkMQ92OOtpsce145obXs19GLURAkYJ92t0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}