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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f169bdf23da95ef20c4425b065f23e8ecc419d270450b49ed49befe482646d' 
  AND token = 'flgHq4etCsPTEDtp4W8Optl2cULmx0LidvXDmgDVGNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}