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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b038ec77a0a8e3b4d1271d163e838b7f5af3722a7e8ec495cc86075a69bf9ea' 
  AND token = 's3up2f2bVQ0M27CPEJvctIjRso9AVbiGJBXMHlphkrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}