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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5d6360127dde7aee40b0c6b3dd3f24f40bb95bde857309a3d8a283c8b7b1f72' 
  AND token = 'YrKImQx99E/hoQzMcdI/Su7ENgBUK8NVCWgLt/ZDdWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}