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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75568fc9270022435404932b31bf40fb3acb0f4c32ee1ee1b5786a56e4f68d0a' 
  AND token = 'kFBJBsrJ9sQrmsamOLEegQL/csTUhs79KwDtR3/TqMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}