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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b16eb27f1d9c9ccf3f1b8539e49d389af9c3ac2122c0ad0163c2f1b1138b8a68' 
  AND token = 'mIZXxeyH0V2/hKFfAU3cMwBKAC+6lWk58hJeFaPDVJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}