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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f474c03f1c5f9fce32f47f4f236c3d3b04f678d63a21143763ce1dce7b2d65e1' 
  AND token = 'iykVYxc6254sHalT4qf+pn1LrwYFnKRNchMEHuI1Gs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}