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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b58b99048ed7d9d10e996e7aba7e666873ffd1cfb8a781c729935354d0d48421' 
  AND token = 'ZnfOu4YTCBh5C8JDuEPvbLcXSdI6Co2qknqHg2Rkf2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}