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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f8d3a9cf875b0453d7161ed92dacc9a953b692f92f3df27e160a31326388231' 
  AND token = 'MIFpedD6yOqO/Td5m74ixSZbUkUFadH/3Yvk30Yno3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}