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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5af02da078874281f945e75001671712dfd2a7eddd315e36faa5deb10337f6d' 
  AND token = 'H3gpxaC99pP1AQFX3xZS5/0M3eXnD4L8igoPRDQ2wV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}