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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e27aca2c7690b82ce0a378d1dfdedc75763fdd9215f8f505d0064fd6a1222c5d' 
  AND token = '+Cj3AsTelLfOxeDjR0Qo3qARfLyr9PtFVdkhJI6erIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}