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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49a8131ed01509f0333a3c5c3b09cf2af7f74c82816b956965e80a922d5d91ac' 
  AND token = '2TdTfvR7z7w0slqQdT4Euj0ykXxj+yXgZiHUMHliLWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}