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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d0b0258ab9c4acafd8649b951d59866034a855eb0bde8e19c08d049040926f6' 
  AND token = 'VhEeH0j9EE8/UY2tB9SVljGmAun0gbf73eMpIh3/eE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}