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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '856efe7f9335cf4d3fbdb0b6461f425d2da4021eebf08fa29cf6eebbf2e752f5' 
  AND token = '0ip7/+37EFlxCM/OqTjHHYvr8rdcRre5GNKCLkcZxkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}