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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '118a12aa17e37eef28c8de8db1d0c65a2b2c0526a1dfad05749dd20302019d4f' 
  AND token = 'yA9bd3ZP1JnWQhvHIu4fSI097CK/r51fSgVbHo4Bo8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}