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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74512bd4af505961970a6da910fe6fe5b0269ae99821f5951504478f91c7b211' 
  AND token = '73UPDVSeKk8/FnEOswptds+0SjfYypIyPWUa5tYJ4WI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}