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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28e486626748c8e57e17cc98695dee884ed6355281054f12e4f40818970fc5d4' 
  AND token = '1Tr6Yr3HJZr3GqYjJcN4VIiB7oyLreWkDUQRtGyQ2ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}