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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12cecbf7e29d2df329e369e64b4a60d2ab4745a788fa77f93540ad7713cb5bab' 
  AND token = 's4BbYH4FeGN0fE8TUaCwJhMbK1YlBZo37R17vabwKD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}