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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '753a739c62c924e1321887003a5824c253bbb45651d2c061e11b1a246d68728b' 
  AND token = 'kPqGj5I4f3V0TNgqkJ7o7X1oCR2USIzMHWFEhrB/JQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}