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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38cd781e281bcee553e55b8510861856da418efd5bee941bae675bdc4c5b4552' 
  AND token = 'ea8JWfSPUCewEbOyaGgiKNkQqWFj4GT7EKOzPQAPHjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}