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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37870fc770188c1d67c43b9df71d2034194c835971f607feef6b22a71f16f4bb' 
  AND token = 'SB6Mq2EGKA2HjfdoTc4dRkLKFchpQq/Ewm6C9GbfLiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}