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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f2b12222e31f6f15c1aa9050b34eefc72531e4a7652c00886c422f293f10995' 
  AND token = 'PZzlWy9B8haxCqCXegV0kifB/WCpcnXBT+zutVZ6LOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}