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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c24311b4024c59532ebaf76cd2dd0c96e9ceed7ae7a2a313003462bf7e0aafc' 
  AND token = 'cv/zxeSwYw8jg8QNix0nvX4WKBKjxbHX9WAfkfsAvVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}