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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6a6dbdaf9a670307237d11293572044a289193a47c09137ea18150a589f706c' 
  AND token = 'exbhemzwMLoF8iwbJeqY+4NisVnZe0KxfuFcTQY8u8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}