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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c8bf254d0298c497506166c54f29f381474607f94429d004d59342246d51185' 
  AND token = 'J7c2k5fKAk3Z+sn4AyTbMJIATtXPnl6sJlgH36V5O+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}