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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59a0cbf8a444ee57be03754d2f00a961d9e6b4f686c1d36b06322264613a0a26' 
  AND token = 'RCQjqqA65H+adjcpN8WAqcdCEzAfHNTihPGrqjCPFfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}