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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee3e51d3de5d01859b89ff73e66446d0d3a9afad97771347efd2f9e3c376ec9e' 
  AND token = 'u0mlfMBXsn01MDJQpq6uUg45KjK2r9I3JrzJYhB4Fa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}