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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe20fdf57cba140376d23da1d0d08942282c0a2c87e1891edb95874941dfdb3d' 
  AND token = '1LYHb3WtBxbhTpsF1/scTgCqTKQxehQuGP1yn+8BFxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}