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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66323b42a6a2c70e5becbdbf8852057750381042c4201522b689ddaa72a54fb4' 
  AND token = 'UqBP9Gglk9A3Wqipw6AYNOpxiEPcd/hg0Vx5ylM6e0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}