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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ca1c9b6f4cee09b85a61b6d36dc60d3da4e52630443347f610951a209cd0ada' 
  AND token = 'EG0QGVPRr/nao1bqvVdj2bwq4jSaj42GnIwUDVl3jE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}