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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d72615da15d63dac9b2f6468758c838a038368280bf6b8f2555695739640960' 
  AND token = '8m/lX3GtaHLEzKE+FElyJGXQiZAZd6tvXYN3eWqK39I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}