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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '458fe35389ac5f9e63a654787ad86e07c183361852515ce954831a014311d5c2' 
  AND token = 'qDOB4Jnie+JqlFGmSi2Tq+h6zn7UU9YMlDJpkfLyWrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}